{"id":7829,"date":"2021-03-21T23:57:32","date_gmt":"2021-03-22T03:57:32","guid":{"rendered":"https:\/\/myendoconsult.com\/learn\/?page_id=7829"},"modified":"2023-06-13T23:56:54","modified_gmt":"2023-06-14T04:56:54","slug":"dynamic-tests-in-endocrinology","status":"publish","type":"page","link":"https:\/\/myendoconsult.com\/learn\/dynamic-tests-in-endocrinology\/","title":{"rendered":"Dynamic Tests in Endocrinology"},"content":{"rendered":"

Dynamic tests in endocrinology are based on an understanding of key regulators of hormonal secretion. A simple rule of thumb is to suppress a hormone if you suspect it is being over-secreted. Conversely, stimulate a hormone if you suspect it is being under secreted or absent.<\/p><\/blockquote>

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Sample infographic of a dynamic test<\/h2>

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This is a sample visual infographic<\/em><\/p>

A Collection of Dynamic Tests<\/h2>

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Cosyntropin (cortrosyn) stimulation test :<\/strong> \u00a0A dynamic test for the evaluation of suspected adrenal insufficiency. The test cannot distinguish between primary and secondary AI<\/p>

Limitations of this test<\/strong>Estrogen in OCPs may increase corticosteroid-binding globulin and thus increase total serum cortisol.Low albumin can lead to a spuriously low serum cortisolIt does not distinguish between primary and secondary AI (normal stimulation test if adrenocortical atrophy has not set in yet)<\/p><\/td>

Print version<\/a><\/td><\/tr>

Growth hormone suppression test :<\/strong> This dynamic test is used for the evaluation of suspected acromegaly<\/strong><\/a>.<\/strong><\/p>

Limitations of this test<\/u><\/strong>GH levels may not be suppressed in patients liver disease, renal insufficiency, uncontrolled DM, pregnancy, estrogen therapy or anorexia.Possibility of a paradoxical increase in GH during an oral glucose tolerance test.<\/p><\/td>

Print version<\/a><\/td><\/tr>
GHRH-Arginine Growth hormone stimulation test :<\/strong> \u00a0This dynamic test is used for the evaluation of suspected growth hor\u00admone deficiency. Alternatives include the ITT <\/strong>and Glucagon stimulation <\/strong>tests<\/td>Print version<\/a><\/td><\/tr>

Glucagon Stimulation Test:<\/strong> \u00a0This dynamic test is used for the evaluation of suspected growth hormone deficiency<\/a>. Alternatives include the ITT <\/strong>and GHRH-arginine<\/strong>.<\/p>

Limitations of this test<\/u><\/strong>Associated with significant nausea and vomiting. As a precaution, patients should therefore be nil per os, except for water, after midnight and during the test. Prophylactic anti-emetics are advised.Risk of hypoglycemia after the test (consuming small meals is reasonable)<\/p><\/td>

Print version<\/a><\/td><\/tr>
Insulin Tolerance Test :<\/strong> \u00a0This dynamic test is used for the evaluation of suspected growth hor\u00admone deficiency<\/strong>. It is a gold standard test for evaluating suspected secondary <\/strong>adrenal insufficiency<\/a>.<\/td>Print version<\/a><\/td><\/tr><\/tbody><\/table>

Pathophysiologic Basis of Dynamic Tests in Endocrinology<\/h2>

MyEndoConsult<\/a><\/span><\/p>

0<\/span><\/p> <\/a>

Oral Glucose Tolerance Test<\/a><\/span><\/h2>

The Oral Glucose Tolerance Test (OGTT), a cornerstone in diagnosing and monitoring <\/a><\/p>

MyEndoConsult<\/a><\/span><\/p>

0<\/span><\/p> <\/a>

Clonidine Suppression Test<\/a><\/span><\/h2>

Clonidine Suppression Test (Infographic)Physiology and Rationale of the Clonidine Suppression TestThe clonidine <\/a><\/p>

MyEndoConsult<\/a><\/span><\/p>

0<\/span><\/p> <\/a>

Water Deprivation Test<\/a><\/span><\/h2>

Indication for the Water Deprivation Diabetes Insipidus, characterized by polyuria and polydipsia, <\/a><\/p>

MyEndoConsult<\/a><\/span><\/p>

0<\/span><\/p> <\/a>

Growth Hormone Suppression Test<\/a><\/span><\/h2>

Figure. Growth Hormone Suppression Test. An infographic summarizing the test procedure and <\/a><\/p>

MyEndoConsult<\/a><\/span><\/p>

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Glucagon Stimulation Test<\/a><\/span><\/h2>

Interpretation of the Glucagon Stimulation TestIndications for the Glucagon Stimulation TestTo evaluate <\/a><\/p>

MyEndoConsult<\/a><\/span><\/p>

0<\/span><\/p> <\/a>

The Levothyroxine Absorption Test: Assessing Thyroid Hormone Malabsorption<\/a><\/span><\/h2>

Levothyroxine Absorption Test (Infographic)Levothyroxine is a synthetic form of the thyroid hormone, <\/a><\/p>

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Dynamic tests in endocrinology are based on an understanding of key regulators of hormonal secretion. A simple rule of thumb is to suppress a hormone if you suspect it is being over-secreted. Conversely, stimulate a hormone if you suspect it is being under secreted or absent. Sample infographic of a dynamic test This is a […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-7829","page","type-page","status-publish","hentry","post-wrapper","thrv_wrapper"],"_links":{"self":[{"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/pages\/7829","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/comments?post=7829"}],"version-history":[{"count":107,"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/pages\/7829\/revisions"}],"predecessor-version":[{"id":4420190,"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/pages\/7829\/revisions\/4420190"}],"wp:attachment":[{"href":"https:\/\/myendoconsult.com\/learn\/wp-json\/wp\/v2\/media?parent=7829"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}