{"id":525890,"date":"2022-01-01T13:30:25","date_gmt":"2022-01-01T18:30:25","guid":{"rendered":"https:\/\/myendoconsult.com\/learn\/?p=525890"},"modified":"2023-03-16T06:04:50","modified_gmt":"2023-03-16T11:04:50","slug":"eye-signs-of-thyroid-disease","status":"publish","type":"post","link":"https:\/\/myendoconsult.com\/learn\/eye-signs-of-thyroid-disease\/","title":{"rendered":"Eye Signs of Thyroid Disease"},"content":{"rendered":"

Thyroid eye disease (TED) is the most common extra-thyroidal manifestation of Graves\u2019 disease. TED can present with a myriad of ocular signs, including photophobia, proptosis, or conjunctival injection. Other signs suggestive of TED include lid lag, globe lag, lid retraction, and even, in some severe cases, evidence of optic neuropathy.<\/p>\n

Clinical findings in Thyroid Eye Disease<\/h2>\n\n\n\n\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t\n\t
Eye sign<\/td>Clinical findings<\/td>\n<\/tr>\n
Dalrymple\u2019s sign<\/td>Lid retraction involving the upper eyelid<\/td>\n<\/tr>\n
Von Grafe\u2019s sign<\/td>Lagging of the upper eyelid upon downward gaze<\/td>\n<\/tr>\n
Collier\u2019s sign<\/td>Lid retraction involving the lower eyelid<\/td>\n<\/tr>\n
Stellwag\u2019s sign<\/td>Infrequent blinking of the eyelids<\/td>\n<\/tr>\n
Rosenbach\u2019s sign<\/td>Tremors of the eyelids upon closure<\/td>\n<\/tr>\n
Gifford sign<\/td>A difficulty with eversion of the upper eyelids<\/td>\n<\/tr>\n
Jellinek sign<\/td>Hyperpigmentation of the upper eyelids<\/td>\n<\/tr>\n
Sainton sign<\/td>Nystagmus on the voluntary horizontal movement of the eyes<\/td>\n<\/tr>\n
Ballet sign<\/td>Paresis of extraocular muscles<\/td>\n<\/tr>\n
Enroth sign<\/td>Periorbital edema<\/td>\n<\/tr>\n
Griffith\u2019s sign<\/td>Lid lag involving the lower eyelid on upward gaze<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n\n

Clinical Pearl<\/h2>\n

Why do patients with Graves\u2019 disease<\/a> have upper eyelid retraction?<\/strong><\/p>\n

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