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A 52-year-old male patient, who is physically inactive and has a BMI of 27 kg/m2, presents to your clinic. He is asymptomatic but mentions that his elder brother was diagnosed with type 2 diabetes. According to the American Diabetes Association (ADA) guidelines, how often should this patient be screened for type 2 diabetes?
Check the ADA guidelines for screening of type 2 diabetes.
A patient with no classic symptoms of hyperglycemia presents with a Hemoglobin A1c (HbA1c) level of 6.3%. According to the American Diabetes Association (ADA) guidelines, how should this patient be classified?
Refer to the ADA's HbA1c criteria for diagnosing diabetes and pre-diabetes.
A 40-year-old woman presents with symptoms of polyuria, polydipsia, and excessive fatigue. A random plasma glucose test shows a glucose level of 205 mg/dL. According to the American Diabetes Association (ADA) guidelines, how can this patient's condition be diagnosed?
Check the ADA criteria for the diagnosis of diabetes using a random plasma glucose test.
A 45-year-old Asian male patient with a BMI of 24 kg/m2 comes to your clinic for a routine check-up. His mother has type 2 diabetes and he does not exercise regularly. He is asymptomatic and is not on any medication. How often should he be screened for type 2 diabetes according to the ADA guidelines?
Consider the ADA guidelines for diabetes screening for overweight or obese adults of any age with additional risk factors.
A 32-year-old woman presents to your clinic for pre-conception counseling. She is obese with a BMI of 30 kg/m2 and has a history of delivering a baby weighing >9 lb. What should be your next step regarding diabetes screening for this patient?
Consider the ADA guidelines for diabetes screening for women planning pregnancy with risk factors for gestational diabetes.
A 28-year-old woman is pregnant with her first child. She is overweight, and her mother has type 2 diabetes. At what point in her pregnancy should she be screened for gestational diabetes according to the ADA guidelines?
Consider the ADA guidelines for gestational diabetes screening for all pregnant women.
A 25-year-old pregnant woman with a history of delivering a baby weighing >9 lb in her first pregnancy comes to your clinic at 12 weeks gestation. She has a BMI of 30 kg/m2. How should her risk of developing gestational diabetes be assessed and when should testing be performed?
Consider the risk factors for gestational diabetes and the recommendations for testing based on the risk.
A pregnant woman is diagnosed with gestational diabetes using the “two-step” approach. Her fasting plasma glucose level is 105 mg/dl, one-hour level is 190 mg/dl, two-hour level is 160 mg/dl, and three-hour level is 145 mg/dl. Which diagnostic criteria were used to diagnose her condition?
Consider the specific values for the glucose levels in different diagnostic criteria for gestational diabetes.
A 35-year-old woman who had gestational diabetes during her pregnancy comes to your clinic 10 weeks after delivery. She has a BMI of 25 kg/m2. What is the recommended approach for postpartum testing for this patient?
Consider the ADA's recommendations for postpartum testing in women with a history of gestational diabetes.
What is the recommended annual screening method for diabetes in individuals over the age of 10 with cystic fibrosis?
What is the gold standard procedure for measuring insulin resistance?
What is the function of c-peptide testing in patients with diabetes?
A 58-year-old woman with type 2 diabetes mellitus presents to your clinic for her regular checkup. She was diagnosed 3 years ago and is currently on Metformin. According to the ADA, how often should her HbA1c levels be checked to monitor glycemic control?
The ADA recommendations for frequency of HbA1c testing.
A 35-year-old African-American man with type 1 diabetes mellitus, currently on insulin therapy, comes to your clinic. What is the recommended target HbA1c level for him according to the American Diabetes Association (ADA)?
ADA goal HbA1c value.
A 70-year-old woman with a history of CKD stage 4 and newly diagnosed diabetes comes to your clinic. She is not yet on any medication. Which assay might not provide an accurate measure of her hyperglycemia?
A test affected by advanced renal disease (CKD stages 4-5).
A 55-year-old patient with a history of Roux-en-Y gastric bypass surgery presents with symptoms of confusion, sweating, and palpitations. His plasma glucose level is found to be 50 mg/dl. Which of the following is a likely cause of his hypoglycemia?
Consider the patient's medical history and the potential causes of hypoglycemia.
A 42-year-old patient has been experiencing symptoms of hypoglycemia. He is scheduled for a prolonged fast to determine the cause. What is one of the main purposes of this test?
The hint is in the name of the test.
A 60-year-old patient with diabetes uses continuous glucose monitoring (CGM) to manage his condition. Which of the following benefits is most associated with the use of CGM?
Consider what information a continuous glucose monitor provides.
A 30-year-old woman presents with symptoms of confusion, sweating, and palpitations. She has a plasma glucose level of 50 mg/dl. Her insulin, C-peptide, and proinsulin levels are all high and there are no oral hypoglycemic medications detected. What is the likely cause of her hypoglycemia?
Consider the different causes of hypoglycemia and their respective clinical signs.
A 40-year-old man is undergoing a prolonged fast to determine the cause of his hypoglycemia symptoms. He is diagnosed after 48 hours. What is the likely cause of his hypoglycemia?
Consider the timing of the diagnosis during the prolonged fast.
A 35-year-old woman is experiencing hypoglycemia symptoms several hours after meals. Which diagnostic test would be most suitable for her condition?
Consider the timing of the patient's hypoglycemia symptoms.
A 45-year-old woman with an inconclusive prolonged fast result is undergoing a glucagon tolerance test. She has a high insulin response with values exceeding 200 uU/ml within 20 minutes of the glucagon injection. What is the most probable diagnosis?
Consider the results of the glucagon tolerance test.
A 60-year-old man with hepatic disease is undergoing a glucagon tolerance test. What kind of response might be expected?
Consider the effect of hepatic disease on glycogen stores.
A 52-year-old man with acromegaly is undergoing a glucagon tolerance test. What kind of response might be expected?
Consider the effect of acromegaly on insulin response.
A 30-year-old Japanese woman is suspected to have autoimmune hypoglycemia. She has high insulin levels, but her C-peptide levels are not suppressed. What is the most probable cause of her hypoglycemia?
Consider the association of high insulin levels and C-peptide levels in autoimmune hypoglycemia.
A 45-year-old woman with a BMI of 27 kg/m2 is undergoing a c-peptide suppression test. What percentage decrease in c-peptide at 60 minutes would be considered abnormal?
Consider the BMI and age of the patient when interpreting the c-peptide suppression test results.
A 35-year-old man with hypoglycemia is suspected of having an insulinoma. However, his c-peptide levels remain normal after a c-peptide suppression test. What can be inferred from these results?
Consider the limitations of the c-peptide suppression test in diagnosing insulinomas.
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