MELD Score

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MELD Score Calculator

Disclaimer: This calculator is for informational purposes only. Clinical decisions should be based on a full evaluation and professional judgment.

How to Calculate the MELD Score

1. Initial MELD

For candidates ≥12 years old, the initial MELD(i) is calculated

  1. Round this to the tenth decimal place.
  2. Multiply by 10 to get the MELD(i) value.

Important: Use serum creatinine, bilirubin, and INR in US units, and sodium in mEq/L. If bilirubin, creatinine, or INR is <1.0, use 1.0 to avoid negative logarithms.

2. Final MELD Calculation (If MELD(i) > 11)

If MELD(i) is greater than 11, an additional step incorporates serum sodium:

Special Rules

  • Creatinine Cap at 4.0:
    • If Creatinine is >4.0, set it to 4.0.
    • If the patient has ≥2 dialysis treatments in the prior 7 days or ≥24 hours of CVVHD in the prior 7 days, use 4.0 as the creatinine value.
  • Sodium Clamping:
    • If Na <125, use 125.
    • If Na >137, use 137.
  • Minimum Lab Values:
    • Bilirubin <1.0 ⇒ use 1.0
    • Creatinine <1.0 ⇒ use 1.0
    • INR <1.0 ⇒ use 1.0
  • MELD Score Maximum = 40:
    • If the calculated MELD exceeds 40, it is typically capped at 40 for the purpose of listing and transplant allocation.

MELD Score Interpretation

Several studies have linked MELD scores with 3-month mortality. The following table summarizes approximate mortality risk:

MELD ScoreEstimated 3-month Mortality
≤91.9%
10–196.0%
20–2919.6%
30–3952.6%
≥4071.3%

Patients with higher MELD scores are at significantly increased risk of mortality, which highlights the urgency for potential liver transplantation or other interventions.


Clinical Pearls

  • Assessment Beyond MELD: While MELD is an excellent predictor of short-term mortality, always consider additional factors such as overall clinical status, comorbidities, and patient support systems.
  • Dialysis and Sodium: Creatinine level and sodium level corrections (dialysis, Na clamp) are critical in accurately determining the MELD score, especially as advanced disease often involves renal impairment and electrolyte disturbances.
  • Maximum Score of 40: Although the formula might produce a higher number, 40 is the recognized ceiling for listing purposes.
  • Pediatric Cases: Patients under 12 years of age use the PELD (Pediatric End-Stage Liver Disease) score, which incorporates different parameters.
About the Author MyEndoConsult

The MyEndoconsult Team. A group of physicians dedicated to endocrinology and internal medicine education.

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