This practical guide presents a concise approach to exploring endocrine pathophysiology through the physical exam, emphasizing common clinical signs in endocrinology that can be elicited through inspection, palpation, percussion or auscultation. 

The established and proposed mechanisms underlying these physical signs are highlighted, allowing students, residents and trainees to better appreciate endocrine pathophysiology at the bedside. 

The text is organized sensibly to facilitate quick and efficient review by medical trainees. Major diseases in endocrinology are grouped by organ systems – pituitary, thyroid, adrenal, and so on. Specific physical examination findings in each primary endocrine disease are reviewed and grouped under the categories of clinical features and pathophysiology, followed by related clinical and pathophysiology pearls.