Opioid Conversion Calculator
Conversion Result:
Note: This calculator is for double-checking opioid conversions and should NOT be used as the sole means for ordering. Always refer to clinical guidelines, patient factors, and professional judgment.
MME Calculation Formula
Formula: MME/day = Dosage1 x Doses per day x MME conversion factor
1Dosage in mcg/hr for fentanyl patch, in mcg for fentanyl buccal/sublingual tablets, and in mg for all other opioids.
1Dosage in mcg/hr for fentanyl patch, in mcg for fentanyl buccal/sublingual tablets, and in mg for all other opioids.
| Opioid | Common Dosages | MME Conversion Factor2 |
|---|---|---|
| Codeine | 15mg, 30mg, 60mg, 2.4 mg/mL, 6 mg/mL | 0.15 |
| FentaNYL buccal or sublingual tablets | 100 mcg, 200 mcg, 300 mcg, 400 mcg, 600 mcg, 800 mcg | 0.13 |
| FentaNYL patch (Duragesic) | 12.5 mcg, 25 mcg, 37.5 mcg, 50 mcg, 62.5 mcg, 75 mcg, 87.5 mcg, 100 mcg | 2.4 |
| HYDROcodone (Vicodin, Norco, Lortab) | 2.5 mg, 5 mg, 7.5 mg, 10 mg, 1 mg/mL, 0.5 mg/mL, 0.667 mg/mL | 1 |
| HYDROmorphone (Dilaudid) | 2 mg, 4 mg, 8 mg, 12 mg, 16 mg, 32 mg, 1 mg/mL | 5 |
| Methadone3 | 5 mg, 10 mg, 40 mg | 4.7 |
| Morphine | 10 mg, 15 mg, 20 mg, 40 mg, 45 mg, 50 mg, 60 mg, 70 mg, 75 mg, 80 mg, 90 mg, 100 mg, 120 mg, 130 mg, 150 mg, 200 mg, 2 mg/mL, 20 mg/mL | 1 |
| OxyCODONE (OxyCONTIN, Roxicodone) | 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 60 mg, 80 mg, 1 mg/mL, 20 mg/mL | 1.5 |
| OxyMORphone | 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 1 mg/mL | 3 |
| Tapentadol3 (mg) | N/A | 0.4 |
| TraMADol (Ultram), mg | N/A | 0.2 |
| Buprenorphine4 | N/A | 10 |
3Conversion of methadone and tapentadol is particularly complex.
4Buprenorphine is a partial opioid agonist and is not expected to be associated with dose-dependent overdose risk in the same manner as full agonist opioids; it is often omitted from MME calculators.
| MME range | Comparative risk* | Recommendation | Annual overdose rate |
|---|---|---|---|
| 1 to <20 MME/day | Reference | Acceptable therapeutic range for acute pain and opioid-naïve patients | 0.2% |
| 20 to <50 MME/day | 2x higher risk of overdose | There is no completely safe opioid dose; use caution at any dose | Data not available |
| 50 to <100 MME/day | 3.7x higher risk of overdose | Strongly consider non-opioid analgesics and decreasing daily opioid dose | 0.7% |
| ≥100 MME/day | 8.9x higher risk of overdose | Consult pain specialist to reassess pain regimen and taper off opioids | 1.8% |
