Diabetes and Endocrinology Trials
Important Trials in Diabetes and Endocrinology 2023
4 Topics
The ONWARDS3 Clinical Trial
Is Testosterone Therapy Safe for the Heart? Insights from the TRAVERSE Study
Retatrutide Clinical Trial
Orforglipron vs. Type 2 Diabetes: A Breakthrough in Oral Treatment?
Important Trials in Diabetes and Endocrinology 2021
14 Topics
Bone Mineral Density and Turnover After Sleeve Gastrectomy and Gastric Bypass.
SURPASS-2: A Study of Tirzepatide Versus Semaglutide Once Weekly as Add-on Therapy to Metformin in Participants With Type 2 Diabetes
STEP 1 : Semaglutide Treatment Effect in People with Obesity
SOLOIST-WHF: Effect of Sotagliflozin on Cardiovascular Events in Patients with Type 2 Diabetes Post Worsening Heart Failure.
SCORED : Effect of Sotagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk
A Placebo-Controlled Trial of Subcutaneous Semaglutide in Nonalcoholic Steatohepatitis
MOBILE : Continuous Glucose MOnitoring in T2D Basal InsuLin UsErs.
Association of metabolic-bariatric surgery with long-term survival in adults with and without diabetes
FIDELIO-DKD: Finerenone in Subjects with Type 2 Diabetes Mellitus and Diabetic Kidney Disease
EMPEROR-Preserved: EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction.
COMPASS: Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia
AMPLITUDE-O: Cardiovascular and Renal Outcomes with Efpeglenatide in Type 2 Diabetes.
AfterDmab: Zoledronic Acid to Maintain Bone Mass After Denosumab Discontinuation.
ACTIVE : Effect of Abaloparatide vs Placebo on New Vertebral Fractures in Postmenopausal Women With Osteoporosis: A Randomized Clinical Trial
Reproductive Endocrinology
8 Topics
WHI E + P
AMIGOS : Letrozole, Gonadotropin, or Clomiphene for Unexplained Infertility
HERS Study
KEEPS Study : Arterial imaging outcomes and cardiovascular risk factors in recently menopausal women: a randomized trial
PCOS (LETROZOLE STUDY)
FET
ELITE – The Early versus Late Intervention Trial with Estradiol
PCOS
Diabetes Mellitus
24 Topics
EMPA-REG OUTCOME : Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes
ELIXA
EDIC
DAPS Study : Denosumab Adherence Preference Satisfaction Study
Calcium and Bone Metabolism
7 Topics
Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial
FIT : Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group
PTH(1-34) : Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
FRAME : Romosozumab Treatment in Postmenopausal Women with Osteoporosis
FREEDOM : Denosumab for prevention of fractures in postmenopausal women with osteoporosis
HORIZON : Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
Zoledronic Acid Recurrent Fracture Trial
Pituitary Disorders
2 Topics
PASIREOTIDE B2305 STUDY GROUP : A 12-month phase 3 study of pasireotide in Cushing’s disease
COPEPTIN – A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus
Lipidology and Obesity
13 Topics
RECORD: Rosiglitazone Evaluated for Cardiovascular Outcomes in oRal agent combination therapy for type 2 Diabetes mellitus
4S : The Scandinavian Simvastatin Survival Study
JUPITER – Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
IMPROVE-IT : Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes
HPS3/TIMI55 : Effects of Anacetrapib in Patients with Atherosclerotic Vascular Disease
HOPE-3 Trial : Cholesterol Lowering in Intermediate-Risk Persons without Cardiovascular Disease
ASCEND : Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus
CONQUER
CAMELLIA-TIMI 61 : Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients
COR1
STAMPEDE : Bariatric surgery versus intensive medical therapy in obese patients with diabetes
ORIGIN N-3 Fatty Acid
ODYSSEY OUTCOMES : Alirocumab and Cardiovascular Outcomes after Acute Coronary Syndrome
Hypertension and Adrenal Disorders
2 Topics
SPRINT
SPYRAL HTN-ON MED
Thyroid Diseases
7 Topics
SCH – Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy.
DECISION STUDY
OPTIC – Treatment of Graves’ Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in a Clinical Study
RAI
TABLET – Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception. Thyroid AntiBodies and LEvoThyroxine study
WDTC
ZETA Study
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Thyroid Diseases
Diabetes and Endocrinology Trials
Thyroid Diseases
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SCH – Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy.
DECISION STUDY
OPTIC – Treatment of Graves’ Orbitopathy to Reduce Proptosis With Teprotumumab Infusions in a Clinical Study
RAI
TABLET – Levothyroxine in Women with Thyroid Peroxidase Antibodies before Conception. Thyroid AntiBodies and LEvoThyroxine study
WDTC
ZETA Study
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