• HRT should not be used for primary or secondary prevention of cardiovascular disease (AHA).
• HRT should not be used in menopausal women for primary or secondary prevention of coronary artery disease (ACOG).
Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA. 1998 Aug 19;280(7):605-13.