Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy.

In contrast to the results from previous observational and underpowered studies, treatment of subclinical hypothyroidism or hypothyroxinemia in pregnancy does not improve neurocognitive outcomes from birth through 5 years of age.

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Reference

Casey, B. M., Thom, E. A., Peaceman, A. M., Varner, M. W., Sorokin, Y., Hirtz, D. G., Reddy, U. M., Wapner, R. J., Thorp, J. M., Jr, Saade, G., Tita, A. T., Rouse, D. J., Sibai, B., Iams, J. D., Mercer, B. M., Tolosa, J., Caritis, S. N., VanDorsten, J. P., & Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal–Fetal Medicine Units Network (2017). Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy. The New England journal of medicine, 376(9), 815–825.