Humira Mechanism of Action
An Overview of Indications of Humira Humira, known generically as adalimumab, is a therapeutic drug used in managing a range of chronic…
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Amylin Analog Mechanism of Action
Physiology of amylin in glucose metabolism Amylin, a pancreatic peptide hormone, contributes significantly to the regulation of glucose metabolism. Upon food ingestion,…
Read articleMechanism of Action of Telotristat
Physiology of Serotonin Serotonin, also known as 5-hydroxytryptamine (5-HT), is predominantly produced by neuroendocrine cells, such as enterochromaffin cells, within the gastrointestinal…
Read articleAmylin Analog Mechanism of Action
Physiology of amylin in glucose metabolism Amylin, a pancreatic peptide hormone, contributes significantly to the regulation of glucose metabolism. Upon food ingestion,…
Read articleAcarbose Mechanism of Action
Physiology of alpha glucosidases in carbohydrate metabolism Alpha-glucosidases represent enzymes found on the brush border of the small intestine, vital for the…
Read articleDPP4 Inhibitor Mechanism of Action
Physiology of the DPP4 enzyme in glucose metabolism Dipeptidyl peptidase-4 (DPP4) is a multifunctional enzyme expressed on the surface of a variety…
Read articleMechanism of Action of SGLT-2 inhibitors
Physiology of Renal Glucose Handling by SGLT-2 transporters Plasma glucose filtration occurs at the glomerulus, after which its re-absorption is carried out…
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Physiological Effects of Insulin
Structure Of Insulin Insulin is a 51 amino acid peptide hormone that consists of two chains (A and B) linked by a pair…
Read articleMechanism of action of GLP-1 agonists
Physiology The term “incretin effect” refers to the amplification of insulin secretion instigated by oral glucose ingestion compared to an equivalent amount…
Read articleMechanism of Action Pioglitazone
Physiology Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear receptor superfamily, a large collection of nuclear hormone receptors that includes thyroid hormone…
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