HAPO: Hyperglycemia and Adverse Pregnancy Outcomes. The HAPO Study Cooperative Research Group
• There is a strong and continuous association between maternal glucose levels below current diagnostic thresholds for gestational diabetes and perinatal complications.
• Fasting plasma glucose >92 mg/dl ,1 hour plasma glucose >180mg/dl and 2 hour plasma glucose >153 mg/dl (IADPSG)
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Reference
HAPO Study Cooperative Research Group, Metzger BE, Lowe LP, Dyer AR, Trimble ER, Chaovarindr U, Coustan DR, Hadden DR, McCance DR, Hod M, McIntyre HD, Oats JJ, Persson B, Rogers MS, Sacks DA. Hyperglycemia and adverse pregnancy outcomes. N Engl J Med. 2008 May 8;358(19):1991-2002.