NICE-SUGAR : Intensive versus conventional glucose control in critically ill patients
A paradigm shift in the treatment of inpatient hyperglycemia of critically ill patients was fueled by the results of this landmark study. An intensive insulin target in ICU patients was previously recommended based on the original study by Van den Berghe et al.
NICE-SUGAR Study Investigators, Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Henderson WR, Hébert PC, Heritier S, Heyland DK, McArthur C, McDonald E, Mitchell I, Myburgh JA, Norton R, Potter J, Robinson BG, Ronco JJ. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009 Mar 26;360(13):1283-97.