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Author: MyEndoConsult

The MyEndoconsult Team. A group of physicians dedicated to endocrinology and internal medicine education.
Board review

Mechanism of action of GLP-1 agonists

Physiology The term “incretin effect” refers to the amplification of insulin secretion instigated by oral glucose ingestion compared to an equivalent amount of glucose delivered intravenously. This effect…

Mechanisms

Mechanism of Action Pioglitazone

Physiology Peroxisome proliferator-activated receptors (PPARs) belong to the nuclear receptor superfamily, a large collection of nuclear hormone receptors that includes thyroid hormone receptors, steroid hormone receptors, the vitamin…

Board review

Glipizide Mechanism of Action

Physiology and Mechanism of Action The KATP channel plays a pivotal role in the regulation of insulin secretion as a function of glucose levels. In a state of…

Mechanisms

Repaglinide Mechanism of Action

Physiology Stages of Insulin Release Following a Meal Insulin is instrumental in controlling high blood glucose levels. It encourages glucose absorption into cells and represses the liver’s glucose…

Mechanisms

Metformin Mechanism of Action

Metformin, a pharmaceutical compound classified as a biguanide, demonstrates a multitargeted mechanism of action, effectively intervening in multiple pathophysiological processes implicated in type 2 diabetes mellitus. • It…